Post-operative ileus reduces the rate of mobilization and may also reduce or delay absorption of drugs administered by the gastrointestinal tract. These changes may be antagonized to a certain extent by administration of prokinetic agents such as cisapride. these alterations are induced partly by surgery, partly by the residual effects of anaesthetic agents, and particularly by opioids administered for post-operative pain relief. ![]() ![]() Gastrointestinal tract motility may be reduced markedly after surgery with delay in gastric emptying.
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